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Friday, July 17, 2020 | History

3 edition of Transgenic mouse methods and protocols found in the catalog.

Transgenic mouse methods and protocols

Marten H. Hofker

Transgenic mouse methods and protocols

by Marten H. Hofker

  • 279 Want to read
  • 21 Currently reading

Published by Humana Press in New York .
Written in English

    Subjects:
  • Transgenic mice,
  • Laboratory manuals

  • Edition Notes

    Statementedited by Marten H. Hofker, Jan M. van Deursen
    SeriesSpringer protocols, Methods in molecular biology -- 693, Springer protocols, Methods in molecular biology (Clifton, N.J.) -- v. 693.
    Classifications
    LC ClassificationsQH442.6 .T724 2011
    The Physical Object
    Paginationxi, 352 p. :
    Number of Pages352
    ID Numbers
    Open LibraryOL25382968M
    ISBN 101607619733, 1607619741
    ISBN 109781607619734, 9781607619741
    LC Control Number2010938364
    OCLC/WorldCa689995205

    Request PDF | Mouse Genetics: Methods and Protocols | Mouse Genetics: Methods and Protocols provides selected mouse genetic techniques and their application in modeling varieties of human diseases. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and Cited by:

    Several complete and comprehensive transgenic manuals provide extremely detailed descriptions of transgenic methodologies and protocols (see suggested readings for more information). For the purpose of this chapter, we will concentrate on the two most common and successful methods of transgenic production: Animals that Arise from Pronuclear. Cold Spring Harbor Laboratory Press; New York: Production of transgenic mouse; pp. – This book is one of the most read lab manuals for the production of transgenic mice. Voncken JW. In: Transgenic Mouse: Methods and Protocols. Hofker MH, van Deursen J, editors. Humana Press; Totawa, New Jersey: pp. 9–Cited by:

    Microinjection - Methods and Protocols. Series: Methods in Molecular Biology. Includes cutting-edge techniques for the study of microinjection and its purposes; Focuses on mouse models for half of the book, with the other half centered on a wide variety of other models; Contains key implementation advice from the experts. Raffaella Corvi, Thomas Hartung, in The History of Alternative Test Methods in Toxicology, Transgenic Assays. Transgenic mouse model tests are possible alternatives to the classical 2-year cancer bioassay (31).The rationale for using transgenic mice in regulatory carcinogenicity testing is that transgenic mouse models may be more sensitive predictors of .


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Transgenic mouse methods and protocols by Marten H. Hofker Download PDF EPUB FB2

In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols. Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and transgenic.

About this book Introduction In Transgenic Mouse Methods and Protocols, Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularly for generating mouse models that will enable us to better understand gene function.

Comprehensive and authoritative, Transgenic Mouse: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field. Show all. Comprehensive and state-of-the-art, Transgenic Mouse Methods and Protocols, Second Edition is the ideal guide for all researchers interested in the latest information about the production and analysis of transgenic and knockout mice.

Product details. Series: Methods in Molecular Biology () (Book ) Hardcover: Brand: Humana Press. Transgenic mouse methods and protocols. of mouse spermatozoa and in vitro fertilization / Naomi Nakagata --Autopsy and histological analysis of the transgenic mouse / Marion J.J.

Gijbels and Menno P.J. de Winther "Provided us with the valuable second edition of Transgenic mouse. A great merit of this book is then the fact. Genetically very similar to the human species, mice play an important role in biomedical research and have served as experimental models for a wide variety of pathologies, including cancer, cardiovascular diseases, and behavioral disorders.

In Transgenic Mouse Methods and Protocols, Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily. Transgenic Mouse Methods and Protocols, 2nd Edition. by Marten H. Hofker, Jan M. van Deursen November The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful.

Transgenic mouse methods and protocols. [Marten H Hofker; Jan van Deursen;] Book, Internet Resource: All Authors / Contributors: Veronique Blanquet, -- and Martin Hrabe de Angelis -- 14 Autopsy and Histologic Analysis of the Transgenic Mouse -- Marion J.J.

Gijbels and Menno P.J. de Winther -- 15 Bone Marrow Transplantations to. Transgenic Mouse Methods and Protocols Marten H. Hofker (auth.), Marten H. Hofker, Jan van Deursen (eds.) The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism.

Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known hensive and authoritative, Transgenic Mouse.

PDF File: Transgenic Mouse Methods And Protocols ad and Read Transgenic Mouse Methods And Protocols 2nd Edition physics problem solver ebook download Mouse Methods And Protocols 2nd Edition Imagine that nail art book free download pdf get such certain ad Free eBook:[PDF] Transgenic Cotton: Methods and Protocols.

Transgenic Mouse Methods and Protocols by Marten H. Hofker,available at Book Depository with free delivery worldwide. With advanced transgenic technologies, they can generate transgenic mice and knockout and knockin mice more efficiently.

(1) As most of transgenic service providers know, one of the drawbacks of using transgenic mice and knockout or knockin mice as model organisms for studying gene functions is the long duration of creating desired mouse lines. Transgenic mouse methods and protocols Item Preview remove-circle Transgenic mice, Mice, Transgenic Publisher Totowa, N.J.: Humana Press Collection Borrow this book to access EPUB and PDF files.

IN COLLECTIONS. Books to Borrow. Books for People with Print :   Transgenesis Techniques: Principles and Protocols (2nd edn) Edited by Alan R Clarke Humana Press Inc, Totowa, New Jersey; pp.

$, hardback. ISBN 0 Cited by: Transgenic Mouse Methods and Protocols covers the production and analysis of transgenic and knockout mice. The book also includes a review of mouse models for a wide range of genetic aberrations associated with human disease.

Many researchers played a crucial role in developing mouse technology to the excellent state of art that has now been. Transgenic mouse - Methods and protocols, 2nd edition Article (PDF Available) in European journal of histochemistry: EJH 55(3) July with Reads How we measure 'reads'Author: Carlo Alberto Redi.

Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols.

Methods. There are two basic technical approaches to produce genetically modified mice. The first involves pronuclear injection into a single cell of the mouse embryo, where it will randomly integrate into the mouse genome.

This method creates a transgenic mouse and is used to insert new genetic information into the mouse genome or to over-express endogenous genes. [PDF] Transgenic Mouse: Methods and Protocols (Methods in Molecular Biology, Vol. ) Transgenic Mouse Methods and Protocols (Methods in Molecular Biology) by Marten H.

Hofker (Repost) Transgenic Mouse Methods and Protocols (Methods in Molecular Biology) by Marten H. Hofker. Techniques for introducing foreign genes into the mouse germ line provide novel approaches for modeling human genetic and chronic degenerative diseases.

Since the initial report in describing transgenic mice, methods for the direct microinjection of DNA into the pro-nuclei of fertilized embryos have become established.Methods in Molecular Biology TM Methods in Molecular Biology TM HUMANA PRESS HUMANA PRESS Edited by Marten H. Hofker Jan van Deursen Transgenic Mouse Methods and Protocols VOLUME Edited by Marten H.

Hofker Jan van Deursen Transgenic Mouse Methods and Protocols Transgenic Mouse Methods and Protocols M E T H O D S I N M O L E C U L A R B .Edited by Melissa A. Larson, Ph.D., Technical Director of the Transgenic and Gene Targeting Institutional Facility at the University of Kansas Medical Center.

This new book, part of the Springer Methods in Molecular Biology Series, contains comprehensive information about a variety of topics related to transgenic mouse production.